Sunday, December 3, 2017

The Impacts of Poor Sleep Health on Cardiac and Brain Health


Walking through campus, an observer might pick up mention of how little sleep everyone is getting (especially during finals period). Although it can be difficult to maintain healthy sleeping habits during periods of stress, a recent study exploring the connection between insomnia symptoms and cardio-cerebral events reiterates the important connection between sleep and overall health.

         In the study, individuals with insomnia symptoms such as difficulty initiating sleep, difficulty maintaining sleep, early-morning awakening, and non-restorative sleep were observed from fifteen studies in thirteen different countries (n=160,087 participants). During follow up periods, positive associations were observed between all of the symptoms (except early-morning awakening) and the risk of cardio-cerebral events. Cardio-cerebral events include disorders such as heart disease and stroke. The increased cardiovascular and stroke risk was 27% for difficulty initiating sleep, 11% for difficulty maintaining sleep, and 18% for non-restorative sleep. Additionally, women fared more poorly than their male counterparts who had the same symptoms. In conjunction with the existence of literature that indicates that women are more prone to having insomnia, this information implies that women, in particular, should pay attention to their sleep quality.

The exact mechanism for these negative impacts isn’t yet fully elucidated. However, a 2004 study points to the presence of a bulk flow mechanism in the brain that is used for neural maintenance activities (clearance of beta-amyloid deposits and cell migration). It could be possible that the insufficient sleep experienced by insomniacs impairs this process and, along with other systemic consequences of sleep deprivation, contributes to negative bodily impacts.



References:
Abbott, N. J. (2004). Evidence for bulk flow of brain interstitial fluid: significance for physiology and pathology. Neurochemistry International, 45(4), 545–552. http://doi.org/https://doi.org/10.1016/j.neuint.2003.11.006

He, Q., Zhang, P., Li, G., Dai, H., & Shi, J. (2017). The association between insomnia symptoms and risk of cardio-cerebral vascular events: A meta-analysis of prospective cohort studies. European Journal of Preventive Cardiology, 24(10), 10711082. http://doi.org/10.1177/2047487317702043

1 comment:

  1. Hello Halimah,

    Thank you for posting this interesting information. This is unwelcome news for me, a chronic “bad sleeper.” I knew of the psychological effects of sleep deprivation and some of the physiological effects, but I did not know about the link between insomnia and cardiovascular disease. I did a little research and found that chronic insomnia was only relatively recently linked firmly with significant medical morbidity, as in cardiovascular disease. Several studies show that a difficulty initiating or maintaining sleep were associated with an increased risk of hypertension, acute myocardial infarction, and incident type 2 diabetes. Compared to normal sleepers who slept ≥ 6h per night, the highest odds of hypertension or diabetes was in patients with insomnia who slept ≤5h and the second highest in patients with insomnia who slept 5-6 h, while patients with insomnia who slept ≥ 6h were not at significantly increased risk of hypertension or diabetes. Bottom line: I need to figure out how to get more sleep!

    References:
    Fernandez-Mendoza, J., & Vgontzas, A. N. (2013). Insomnia and Its Impact on Physical and Mental Health. Current Psychiatry Reports, 15(12), 418. http://doi.org/10.1007/s11920-013-0418-8

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